Aspirin Active Pharmaceutical Ingredient (API) Synthesis Practice Device

Aspirin, also known as acetylsalicylic acid, is a long-standing antipyretic and analgesic drug that has been in use for over a century. It has become one of the three classic drugs in the history of medicine and remains the most widely used antipyretic, analgesic, and anti-inflammatory drug worldwide today. Additionally, it serves as a standard preparation for comparing and evaluating other pharmaceuticals. The synthesis process of aspirin active pharmaceutical ingredients (API) involves multiple chemical engineering operation units; therefore, developing a teaching and practical training device for the synthesis and production of aspirin API holds significant practical importance for vocational colleges and higher education institutions.

​Public Unit​

  1. Provides stable softened water, cooling water, compressed air, and vacuum.
  2. Adopts on-site touchscreen operation to achieve automatic main control, combined with partial manual operations to enhance hands-on skills.
  3. Capable of continuous operation and unattended running.
  4. Equipment appearance and dimensions: Constructed with a high-quality aluminum alloy frame and casters, with overall dimensions no larger than 2200mm×1120mm×2050mm (length×width×height).

​Reaction Unit​

  1. Equipped with a quantitative feeding function.
  2. Supports experimental operations for the acylation reaction system and neutralization operations.
  3. Features condensation reflux, filtration separation, and vacuum transfer functions.
  4. The reaction kettle and neutralization kettle are transparent and visible, facilitating observation of experimental phenomena.
  5. Adopts on-site touchscreen operation for automatic main control, combined with partial manual operations to enhance hands-on skills.
  6. Equipment appearance and dimensions: Constructed with a high-quality aluminum alloy frame and casters, with overall dimensions no larger than 2200mm×1120mm×2800mm (length×width×height).

​Recrystallization Unit​

  1. Equipped with a quantitative feeding function.
  2. Enables product purification operations.
  3. Features condensation reflux, filtration separation, and vacuum transfer functions.
  4. Equipment appearance and dimensions: Constructed with a high-quality aluminum alloy frame and casters, with overall dimensions no larger than 2200mm×1120mm×2200mm (length×width×height).

​Packed Distillation Unit​

  1. Supports batch distillation and continuous distillation, with adjustable reflux ratio operations.
  2. The reboiler can be controlled via constant power or pressure self-control to meet diverse distillation needs for different materials.
  3. Requires centralized exhaust of distillation tail gas during the process, with no escape during intermediate stages.
  4. Equipment appearance and dimensions: Constructed with a high-quality aluminum alloy frame and casters, with overall dimensions no larger than 2200mm×1120mm×2285mm (length×width×height).

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